Nkọwa
Topirastat etiti 2-cyanoisonicotinic acid, CAS No. 161233-97-2.A makwaara ngwaahịa a site na aha ndị ọzọ: 2-cyanopyridine-4-carboxylic acid, 2-cyano-4-pyridinecarboxylic acid, na 4-pyridinecarboxylic acid, 2-cyano-.Usoro ihe omimi nke ogige etiti a bụ C7H4N2O2 na ịdị arọ molekụla bụ 148.1189.Ọ bụ ihe dị mkpa na njikọ nke topirastat (ọgwụ eji agwọ hyperuricemia na ndị ọrịa gout).
2-Cyanoisonicotinic acid na-arụ ọrụ dị mkpa na mmepụta nke topirastat, nke na-arụ ọrụ site na igbochi xanthine oxidase, enzyme na-etinye aka na mmepụta uric acid.N'ihi ya, ọkwa uric acid dị n'ọbara na-ebelata, na-ebelata mgbaàmà ndị ọrịa gout.Ngwakọta dị n'etiti a bụ isi ihe na-emepụta usoro nke topirastat, na-eme ka ọ bụrụ akụkụ dị mkpa nke ụlọ ọrụ ọgwụ.
Họrọ Anyị
JDK nwere ụlọ nrụpụta klaasị mbụ yana akụrụngwa njikwa ogo, nke na-emesi nnabata nke etiti API kwụsiri ike.Ndị otu ọkachamara na-emesi R&D obi ike maka ngwaahịa a.megide abụọ, anyị na-achọ CMO & CDMO n'ime ụlọ na mba ahịa.
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