Nkọwa
Anyị methyl 2-methoxy-4-aminobenzoate bụ isi etiti na mmepụta nke lenvatinib, nke a na-eji agwọ ọrịa thyroid na akụrụ.Ngwakọta dị n'etiti a na-arụ ọrụ dị mkpa na ụlọ ọrụ ọgwụ dịka ọ bụ isi ihe maka njikọ nke lenvatinib.
Ngwakọta ahụ, nke nwere nọmba CAS nke 27492-84-8, mara maka ịdị ọcha dị elu na ntụkwasị obi ya.A na-arụpụta ya site na iji teknụzụ kachasị ọhụrụ na njikwa njikwa siri ike iji hụ na ọ na-emezu ụkpụrụ ụlọ ọrụ kachasị elu.Anyị lenvatinib intermediate 2-methoxy-4-aminobenzoic acid methyl ester dị na batches ma dabara maka nnukwu mmepụta ọgwụ.
Anyị methyl 2-methoxy-4-aminobenzoate bụ ọcha na-acha ọcha crystalline ntụ ntụ na-adị mfe soluble na organic solvents.Ọ nwere nnukwu ngwa na ụlọ ọrụ na-emepụta ọgwụ ma mara ya maka ịdị ọcha na nkwụsi ike ya.A na-eji nlezianya chịkọta ogige ahụ iji hụ na iguzosi ike n'ezi ihe n'oge nchekwa na mbupu, na-ekwe ka ndị ahịa anyị dabere na àgwà ya na-agbanwe agbanwe.
Họrọ Anyị
JDK nwere ụlọ nrụpụta klaasị mbụ yana akụrụngwa njikwa ogo, nke na-emesi nnabata nke etiti API kwụsiri ike.Ndị otu ọkachamara na-emesi R&D obi ike maka ngwaahịa a.megide abụọ, anyị na-achọ CMO & CDMO n'ime ụlọ na mba ahịa.
